What is XLH
What is XLH
Symptoms of XLH in adults
XLH affects every adult differently
The symptoms of X-linked hypophosphatemia (XLH) vary from person to person. They can appear at any age and can worsen or change over time. Symptoms affect children and adults differently.
Adults with XLH may experience symptoms in childhood and new symptoms later in life
These include complications such as increased risk of pseudofractures, osteoarthritis, the hardening of ligaments or tendons, as well as a variety of other musculoskeletal symptoms, including pain and stiffness that can decrease mobility and impact daily function.
Symptoms of XLH in adults
Symptoms in adults may include:
Osteomalacia
(weakening of mature bone)
Short stature
Bone and joint pain
Bowed legs and knock knees
Irregularities in walking/balance
(gait abnormalities)
Muscle pain and weakness
Dental abscesses
Tooth loss
Irregularities in the shape of the head
(craniosynostosis)
Headaches
often due to structural defects in the back of the skull (Chiari malformations)
Hardening of ligaments or tendons
(enthesopathy)
Narrowing of spaces in the spinal column
(spinal stenosis)
Osteoarthritis
Fractures and pseudofractures
(areas of bone weakened by a lack of certain minerals)
Hearing loss
Fatigue
My favorite activities for making my stiffness more manageable are taking my dog on walks and doing yoga stretches.”
Cheryl
Living with XLH
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